Uses / Indications: Pyrigesic 1000mg Tablet is used for pain relief and fever. It is used to relieve pain in conditions like headache, joint pain, muscle pain or dental pain.

Product composition:
• Paracetamol / Acetaminophen (1000mg)

Pregnancy interaction:
• Pyrigesic 1000mg Tablet is safe to use during pregnancy.Adequate and well-controlled human studies have shown low or no risk.

Expert advice:
• Good for pain relief and fever but not effective in joint pain due to poor anti-inflammatory action. Starts working within one hour. Wait for at least 4 hours before taking the next dose. Present in many over-the-counter (OTC) and prescription medicines. Avoid taking more than one paracetamol product at a time to prevent overdose. Doses >4 g/day (2 g in alcoholics) may cause liver, kidney or heart problems. Discontinue Pyrigesic and inform your doctor immediately if rash occurs. For children, measure the doses of liquid Pyrigesic using the measuring cup instead of a teaspoon to avoid under or over-dosage. Avoid excess alcohol intake (>3 glasses/day) when taking Pyrigesic as it may cause liver damage.

Side Effects:
• Allergic reaction.

How to use:
• Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyrigesic 1000mg Tablet is to be taken with food.

How it works:
• Pyrigesic 1000mg Tablet is a pain reliever (analgesic) and fever reducer (antipyretic). It works by blocking the production of the chemical messengers (prostaglandins) that transmit pain signals and induce fever.

Faq for medicine:
• Can I take Pyrigesic with vitamin B complex? : Yes, Pyrigesic can be taken with vitamin B-complex preparations. They have been used together in the treatment of acute and painful diseases affecting nerves like trigeminal neuralgias, post-operative pain, etc. Pyrigesic helps to relieve pain and vitamin B-complex corrects the deficiency that might be causing your symptoms.|Is Pyrigesic use associated with Helicobacter pylori infection? : No, Pyrigesic use is not associated with Helicobacter pylori infection. Painkiller drugs can increase the acid secretion in the stomach, aggravate the symptoms of this infection and the risk of stomach and the intestine ulcer. However, this risk is minimum with Pyrigesic as compared to other pain killers.|Can I take Pyrigesic with fexofenadine? : Yes, Pyrigesic can be taken safely with fexofenadine. No drug-drug interactions or any harmful effects have been reported. These are used together to treat the symptoms of cold, cough, flu or a sore-throat and other allergic or viral diseases. Fexofenadine helps to relieve sneezing, runny nose, itchy throat, or eyes and Pyrigesic helps to relieve pain or fever.|Can I take Pyrigesic with warfarin? : Pyrigesic is safe to use occasionally with warfarin as other painkillers like ibuprofen and aspirin can increase the risk of bleeding. However, on a long-term use, Pyrigesic can also increase the risk of bleeding. Talk to your doctor before taking them together as you may need to be monitored regularly.|Can I take Pyrigesic with tamsulosin? : Pyrigesic can be taken with Tamsulosin. No harmful side effects or other interactions have been seen when they are taken together. Tamsulosin is an alpha adrenergic receptor blocker used to treat symptoms of benign prostatic hyperplasia.|Can I take Pyrigesic with cetirizine? : Yes, Pyrigesic can be taken safely with cetirizine. No drug-drug interactions or any harmful effects have been reported. These are used together to treat the symptoms of cold, cough, flu or a sore throat and other allergic or viral diseases. Cetirizine helps to relieve sneezing, runny nose, itchy throat, or eyes and Pyrigesic helps to relieve pain or fever.|Can I take Pyrigesic with ibuprofen? : Yes, Pyrigesic can be taken with ibuprofen. Both help to relieve pain and fever and ibuprofen also decreases inflammation and swelling. However, both increase the acid secretion in the stomach and can cause acid reflux, heartburn, stomach, and intestinal ulcers and gut bleeding on long-term use. |Does Pyrigesic cause weight loss? : Pyrigesic is not known to cause weight loss. It is a very safe medicine for short term use and can cause minor and rare side effects like low blood pressure, and allergic reactions. |Can anyone be allergic to Pyrigesic? : Yes, there have been reports of hypersensitivity and allergic reaction with the use of Pyrigesic. Symptoms of an allergy include swelling of the face, mouth, and throat, shortness of breath, urticaria, red rash, and severe itching. Stop taking Pyrigesic if you have such symptoms and immediately consult your doctor.|How beneficial is to use Pyrigesic with diclofenac? : Pyrigesic and Diclofenac might be given together in case of fever and pain. Pyrigesic has an early onset of action and it helps in relieving the symptoms till diclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, heartburn, and stomach ulcers and bleeding.|Can I take Pyrigesic for stomach pain? : No, Pyrigesic should not be taken for stomach pain. You must consult your physician for this. The stomach pain could be due to some underlying condition, which needs attention.|Can I take Pyrigesic with aceclofenac? : Yes, Pyrigesic can be given with aceclofenac for fever and pain. Pyrigesic has an early onset of action and it helps in relieving the symptoms till Aceclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, heartburn, and stomach ulcers and bleeding.|Does Pyrigesic treat sore-throat : Pyrigesic does not treat sore-throat, flu or cold but it can help in relieving fever and body aches associated with these conditions.|Can I take Pyrigesic with codeine? : Pyrigesic and codeine can be taken together. No drug-drug interactions or any harmful effects have been reported when they are used together. They are commonly given together for the relief of mild to moderate pain due to different reasons.|Does Pyrigesic help a cough? : No, Pyrigesic does not help in the relief of cough but it can help in relieving associated fever and body aches.|Does Pyrigesic contain alcohol? : No, Pyrigesic does not contain any alcohol.|Can I take Pyrigesic with amoxicillin? : Pyrigesic and amoxicillin can be taken together. Amoxicillin is an antibiotic and is used to treat bacterial infections. Pyrigesic is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.|Does Pyrigesic have side effects? : Pyrigesic is quite safe for short term use. It has side effects if taken in more than the dose advised and for a long-term. Immediately consult a doctor if there is nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice as it could be due to an overdose of Pyrigesic.|Is Pyrigesic safe to use? : Pyrigesic is safe to use in the dose as advised by the doctor. Use in more than recommended doses can do serious harm.|Is it safe to take Pyrigesic with erythromycin? : Pyrigesic and Erythromycin can be taken together. Erythromycin is an antibiotic and is used to treat bacterial infections. Pyrigesic is given along, for the relief of associated fever. No drug-drug interactions or any harmful effects have been reported when they are used together.|Is Pyrigesic an antibiotic? : Pyrigesic is not an antibiotic. It's an analgesic (pain-killer) and antipyretic (for the relief of fever), whereas an antibiotic is useful for the treatment of infections.|Can I take Pyrigesic with metronidazole? : Pyrigesic and Metronidazole can be taken together. No drug-drug interactions or any harmful effects have been reported when used together.|Can I take Pyrigesic with homeopathic medicine? : Ask your doctor before taking Pyrigesic with homeopathic medicine as there is no information available on this.|Is it safe to take Pyrigesic with Tramadol? : Yes, Pyrigesic can be taken with Tramadol. They are used together for moderate to severe pain in various diseases and their use is associated with common side effects like nausea, dizziness, and sleepiness.No drug-drug interactions have been reported when they are used together.|Can I take Pyrigesic with Azithromycin? : Pyrigesic and Azithromycin can be taken together. Azithromycin is an antibiotic and is used to treat bacterial infections. Pyrigesic is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.|Is it safe to take Pyrigesic with Naproxen? : Yes, Pyrigesic can be taken with Naproxen. Both are painkillers and belong to the group of non-steroidal anti-inflammatory drugs (NSAIDs) and are used to relieve pain and fever. However, long-term use affects the stomach lining and increase acid secretion which can lead to side effects like acid reflux, heartburn, stomach, and intestinal ulcers and bleeding. |Can a patient with high blood pressure take Pyrigesic? : Occasional use of Pyrigesic is safe in patients with high blood pressure. However, if it is to be taken for a long time, you must talk to your doctor. Pyrigesic belongs to the group of painkillers called analgesics and antipyretics and these drugs can decrease the action of medicines taken by the patient for control of high blood pressure. |Does Pyrigesic interact with vitamin C? : Vitamin C can be taken with Pyrigesic. However, vitamin C increases the blood levels of other drugs similar to Pyrigesic, so it is advised to talk to your doctor if you have to take both these medicines for a long-term.|What happens if you take an overdose of Pyrigesic? : Overdose of Pyrigesic can cause potentially life-threatening liver damage, which is the most serious side effect. Early symptoms may include nausea, vomiting, profuse sweating, and general tiredness. Kidney damage, decreased platelet count and coma may also occur. Immediately consult a doctor or consult an emergency in the case of suspected overdosage.|Can I take Pyrigesic with hyoscine? : Yes, Pyrigesic and hyoscine can be taken together. Hyoscine is used to relieve pain and cramps of the stomach, gut, urinary bladder and urinary tract while Pyrigesic is used to relieve mild to moderate pain of a headache, toothache, muscle pain, joint pain, and fever. Together they can be advised by a doctor for painful conditions of the gut and urinary tract.|Can I take Pyrigesic with Betahistine? : Pyrigesic can be taken with Betahistine. There are no reported drug-drug interactions or harmful effects when they are used together.|Can I take Pyrigesic with rabeprazole? : Pyrigesic and Rabeprazole can be taken together. Rabeprazole is used to prevent Pyrigesic (painkillers) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no clinically significant drug-drug interactions or harmful effects seen when they are used together.|How beneficial is to take urofollitropin alpha with Pyrigesic? : Urofollitropin alpha is given as a subcutaneous injection with the human chorionic gonadotropin (hCG) hormone to assist in ovulation and fertility. Urofollitropin alpha can cause abdominal or pelvic pain or pain and swelling at the injection site in some patients which can be relieved by taking Pyrigesic.|Can vitamin D be taken safely with Pyrigesic? : Yes, vitamin D can be taken with Pyrigesic. Patients with osteoarthritis who are on vitamin D and calcium may need to take Pyrigesic for the relief of any associated pain. No drug-drug interactions or any harmful effects have been reported. |Can I take clindamycin with Pyrigesic? : Pyrigesic and Clindamycin can be taken together. Clindamycin is an antibiotic and is used to treat bacterial infections. Pyrigesic may be given along, for the relief of associated fever. No drug-drug interactions have been reported clinically. However, both are known to cause liver damage. Talk to your doctor if you need them for a long time.|Does Pyrigesic affect the liver? : Use of Pyrigesic for a long time and above recommended doses can cause liver damage ranging from abnormal liver tests to liver failure. If you are taking Pyrigesic from a long time and have nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice, inform your doctor as these could be signs of an underlying liver damage.|Can I take Pyrigesic if I have hepatitis? : Pyrigesic is considered the safest painkiller to take for people with hepatitis for mild to moderate pain and fever. However, Pyrigesic is metabolized in the liver, so, consult your doctor before taking Pyrigesic if you have hepatitis as it can cause liver damage if taken in higher doses or for a very long time.|What are the serious side effects of taking excess Pyrigesic? : Potentially severe life-threatening liver injury is a serious side effect seen with an overdose of Pyrigesic. Overdose can also cause kidney injury, coma, and decreased platelet count. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of suspected overdose.

Medicine interaction:
• Pyrigesic with Oxyphenbutazone|Pyrigesic with Nimesulide|Pyrigesic with Metamizole / Dipyrone|Pyrigesic with Rifampicin|Pyrigesic with Metoclopramide|Pyrigesic with Warfarin|Pyrigesic with Acenocoumarol / Nicoumalone|Pyrigesic with Phenindione|Pyrigesic with Chloramphenicol